Quote:
Originally Posted by elf
Ina, do you know if this test is based on QTL or already on one or more genes ?
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Well, I will try to translate the few informations I have:
The test is able to verify the genomic HD-Breeding-Value. For that 17 marking-genes are selected out of the genom of a dog. The Probability of the occuring of HD and with that of the heritibility can be calculated out of the amount and kind of this markers.
This test has been developed by Prof. Dr. Ottmar Distl of the Institut für Tierzucht und Vererbungsforschung der TiHo Hannover it is available for GSH, it will be a model for other breeds in future. They are working at tests for ED, Cauda Equina, heart diseases and heriditary deapthness in Dalmatians and Epilepsi and heriditary Eyediseases.
The markertest can only be done together with x-rays at the moment. The genomic-breeding-value-estimating is only telling the propability of the occuring of HD and it´s heritibility. The succes of a genomic HD-selection has to be tested in future.
For joining the tests representativ amounts of EDTA-Blood of a breeding population are needed, together with the breeding-book-datas and informations about the anchestors of the breed. For breeds with smaller populations about 200-300 animals are needed. 50% of those animals have to be HD-free, 50% C to E. The time needed for this evaluation is 6-12 month. Interested breeding-clubs can get informed and register under:
www.tierzucht-hannover.de
At the moment there is a long waiting list and for CSW I would suggest to do it with an international population because we only have about 400 dogs here in Germany and won´t have enough dogs for the test but we will talk about it in our club and who is interested can contact me.
regards Ina