chi ha voglia di capirne di più può crearsi le proprie basi in genetica, capire cosa solo le ricerche sui Genetics Markers, leggere qui di seguito e decidere poi se aspettare con più o meno speranza, con derisione o rassegnazione.
http://www.pubmedcentral.nih.gov/art...?artid=1410725
http://bakerinstitute.vet.cornell.ed....php?%20id=178
On 2007, with grant support from the Morris Animal Foundation and Pfizer Incorporated, Dr. George Lust and colleagues Dr. Rory Todhunter, Steven Friedenberg and Dr. Zhiwu Zhang discovered the first panel of genetic markers that could lead to genetic testing for the diagnosis of canine hip dysplasia. With a new sample of dogs, they plan to verify the accuracy of this panel of genetic markers for hip conformation that can predict the breeding value of the dog.
A breakthrough in diagnosis, these genetic tests are expected to be more accurate than current procedures, less expensive to perform, and enable earlier identification of both normal dogs and those at risk for hip dysplasia. Genetic tests may also reduce the need for progeny testing. “This has been a long-sought goal,” says Dr. Lust. “Now, with one DNA sample we are on the road to telling if a young dog will develop normally. We will not need to wait until the dog is old enough to undergo the current radiographic screening.”
The research team also identified a mutation in the gene for fibrillin 2 that segregates in a sample of dysplastic dogs and non-dysplastic dogs.
Fibrillin 2 is a gene expressed in the tissue of hip joints. This is the
first gene reported to be associated with canine hip dysplasia. The discovery opens
opportunities for defining the biochemical basis of the disease.
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