I am not Mijke but I read publications in vet-magazins about it and tried to find out more since almost a year.
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Originally Posted by canislupus
She also told me, that she does not trust in a test based on just 200 blood samples. For the german shepherd test they had thousands of blood samples.
@Mijke: what do you think about this? I am not experienced with validation of those tests. Is she right? How can we get to know if the test will be really good or if there will be more or less wrong results. (before we have to pay lots of money...)
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When they did the GSH-test there wasn´t any test workin at all, when you have a test you can see by much smaller numbers if there is a correlation, to find out if there is a correlation they need the 24 dogs, if there isn´t any correlation they anyway won´t carry on. The 24 dogs will cost only 7 Euros each. If we stop there and wait how things show in future we still would have the possibility to carry on later.
The most important question is how much the test results correlate with the breeding results, to know that we would need to know how long the GSH do select with this test and if the HD-statistics show a signific decrease of HD,
Quote:
Originally Posted by canislupus
She told me to think about spending so much money on a maybe not very good test or maybe better talking to some Experts for genetics and work together with them.
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The test was validated by the genetic institute of a veterinary university by experts on dog-genetics.
Quote:
Originally Posted by canislupus
so, what´s the right way?
Tanja
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I think this is the point when everybody who knows about labs that do databases or knows about genetic projects on dogs should try to find out about the conditions of those labs.
We should start with a database as soon as possible and keep informed about all research projects.
I also think we should keep in touch with the HD-test in Hannover and find out how to raise funds for research. And we can only do all of this on an international basis. Research on dog genetics goes on worldwide.
So it makes sense to now collect people and dogs that are willing to cooperate. If we have a database with all informations research projects do need we could start at once. To build up an international database will take a lot of time.
What seems to be not that clear is even if tests like that in Hannover do work and show a signific benefit, the validation of this kind of test takes 1-2 years. If we build up a new group of people and a new database and so on for every test of interest we all won´t live when the first test can be started.
It makes most sense to build up a database in the best lab we can find for this and have everything ready when there is a project of interest.
Ina