Quote:
Originally Posted by Admin
Yes, thats right. And especially the "unofficial" results can help to correct it. We had some cases where the puppies of a DM/DM dog get the result N/N. Almost nobody cared about it - they were sure that it is OK (because of "mutation"). But it was NOT. In all every case it was mistake made by the laboratory.
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Well, the probability of revert mutation (one from wrong to the right allelle) really is infinitisimmal. But, mutation from right to wrong is possible, although usually not recognized by standardized tests (the one which test for a certain mutation, which is easier than to sequence whole gene of interest to see if abnormalities apper). So you can explain a sudden presence of new phenotype by a mutation, although the probability is still very small.
What I could agree with would be not "DM/N, unofficial result", but "this dog should test DM/N based on parent/offspring results".