HD & CsV

[elf]

A statistique about HD results among CsV (1500 CsV), as a statistique it's not 100% accurate, nevertheless qualitatively informative:

A+B = 75,44%
C+D+E = 24,56%

Not better than GSD (19,1% for the OFA). I think it's time to think where the "wolf vigour" is gone.

[michaelundinaeichhorn]

I hope that a DNA-Test for HD will bring some improvement. But when I look at some matings it will only work when the FCI gives a general rule how to use it for breeding you definetly can´t rely on the breeders. The test is tested on the GSH-population at the moment and will be available for all breeds in some years.

But When you compare statistics you have to be very carfull, I don´t know who the OFA is but the German SV classifications differ from the usual ones, at least some years ago - and as far as I know till today - they have A1 for the normal A, A2 for the normal B and A3 for the normal C, what gives you a very high percentage of A´s.

Ina

[elf]

I took GSD stats from the Orthopedic foundation for Animals: http://www.offa.org/hipstatbreed.html

[michaelundinaeichhorn]

Thank you for the link, it´s very interesting. There is a Hybrid in there with around 20%, if this is wolfhybrids it would be interesting which kind of and which generations.
And it also would be quite interesting to do some research on wild wolves, cause as far as I know there are only very few researches on captive ones. They don´t move that much and it is known that reducing the aktivity results in less HD so we don´t seem to know the real situation in wolves in itself.

Ina

[elf]

I thought wild wolves were almost all HD free helped by natural selection. I saw only one publication: E. M. Douglass. Hip dysplasia in a timber wolf. Vet Med Small Anim Clin, 1981;401-3.

[michaelundinaeichhorn]

This is a theorie and a very likely one but not a proven one as far as I know.
Up to grade C the wolf won´t have any problems till the avarage age so I really have doubts that all wolves are A.

[elf]

Originally Posted by michaelundinaeichhorn

The test is tested on the GSH-population at the moment and will be available for all breeds in some years.

Ina, do you know if this test is based on QTL or already on one or more genes ?

[michaelundinaeichhorn]

Originally Posted by elf

Ina, do you know if this test is based on QTL or already on one or more genes ?

Well, I will try to translate the few informations I have:
The test is able to verify the genomic HD-Breeding-Value. For that 17 marking-genes are selected out of the genom of a dog. The Probability of the occuring of HD and with that of the heritibility can be calculated out of the amount and kind of this markers.
This test has been developed by Prof. Dr. Ottmar Distl of the Institut für Tierzucht und Vererbungsforschung der TiHo Hannover it is available for GSH, it will be a model for other breeds in future. They are working at tests for ED, Cauda Equina, heart diseases and heriditary deapthness in Dalmatians and Epilepsi and heriditary Eyediseases.
The markertest can only be done together with x-rays at the moment. The genomic-breeding-value-estimating is only telling the propability of the occuring of HD and it´s heritibility. The succes of a genomic HD-selection has to be tested in future.
For joining the tests representativ amounts of EDTA-Blood of a breeding population are needed, together with the breeding-book-datas and informations about the anchestors of the breed. For breeds with smaller populations about 200-300 animals are needed. 50% of those animals have to be HD-free, 50% C to E. The time needed for this evaluation is 6-12 month. Interested breeding-clubs can get informed and register under:
www.tierzucht-hannover.de

At the moment there is a long waiting list and for CSW I would suggest to do it with an international population because we only have about 400 dogs here in Germany and won´t have enough dogs for the test but we will talk about it in our club and who is interested can contact me.

regards Ina

[elf]

There is a Hybrid in there with around 20%, if this is wolfhybrids it would be interesting which kind of and which generations.

OFA answer:

"Most hybrid's are either Goldendoodles or Labradoodles.

Thank you for your inquiry.

G.G. Keller, D.V.M., MS
Diplomate ACVR
Chief of Veterinary Services
Orthopedic Foundation for Animals"

[michaelundinaeichhorn]

Originally Posted by elf

OFA answer:

"Most hybrid's are either Goldendoodles or Labradoodles.

Thank you for your inquiry.

G.G. Keller, D.V.M., MS
Diplomate ACVR
Chief of Veterinary Services
Orthopedic Foundation for Animals"