DM test results and breeders

mijke · 14-11-2010, 23:30

Reading other topics about DM on wolfdog, I did see a lot of blaming of breeders in relation of DM test results...

But it is soooooo silly to blame specific breeders when it is known DM did appear in their lines.

In first place you stimulate owners and breeders in future only to publish the " Free" results (because otherwise they will receive comments) And then we can never see how DM is spread in the breed!
And second: Only since a short time we have the DM test for the CsW breed. (nobody even did know before that this disease was in the breed!)
So in the past a lot of combinations can be made with a high risk for DM, without knowing by anybody....

I'll give you my personal example:
I did import my CsW female from CZ. When she was grown up, we did see she had a good character, HD A and several good show results. (in that time dwarfism and DM test did not exist) And we did decide to breed with her. I did look for good combinations and for one of her litters I did use a male from SK.

The last years I did spend a lot of time to get validated the Dwarfism and DM test for the CsW breed.
And when these test were possible for CsW breed I also did test my (already sterilized) female. She was Free of Dwarfism and carrier of DM.

From the litter with the SK male one of the offspring was carrier of DM. And 2 days ago I did receive the result of a female of this litter and she was affected. (DM/DM)

So also the male from SK that I did use was unfortunately also carrier..
And it means also that I am also a breeder of an affected DM/DM CsW.

So `breeder blamers` you also now can start shooting at me!

Personal I only can hope that the affected female never will get the physical problems of DM.
But I can´t change the history! Just like a lot of other breeders I did my best to make the best combinations for the breed with my female.

I am convinced that in future more DNA test will be available for the CsW breed. And it will become more difficult to make the right combinations for the breed. (that will depend of a lot of factors)
But I hope everybody realizes that it on that moment it will be also silly to blame breeders for combinations they did make in the past!

On this moment only an extreme low percentage of the CsW breed is yet tested!!!!

And when dog combinations for new litters are not tested, it does not mean there was/is NO DM in these lines......

So for now it is only important that as much as possible CsW's will be tested

And again:

DM is an old disease that exists in every breed and also in other not breed dogs
Not all DM affected dogs get physical problems
Probably creates a combination of more factors that a dog will get the physical problems

Breeding of breed dogs is a closed system
When higher homozygote in a breed : more genetic diseases, more behavior problems, less resistor, weaker performance, less vitality, more birth dead, and smaller litters
Heterozygote is needed for a healthy population of a breed!

So as told before in other topics, the advice of genetic specialists:
Try to breed as less Affected dogs as possible

But don't exclude dogs for breeding!

Try to keep the gene poule as broadly (and maximize) as possible

Everybody has to realize there is not any reason for "blind panic" about DM!!
But also in CsW breed it seems to be "an old disease" that did start in the past.
And probably it did start in earlier lines in countries of origin and a lot more CsW's can be Carrier or Affected.

So it will be good to test a lot more CsW's for DM!
Only then we can see how DM is spread in the breed and try to avoid that more Affected CsW's will be born!

On this moment it would not be clever to make specific breeding rules based on the relative few CsW that have DM test results !
Especially when not everything is known about this disease.

But for the future of the breed it is necessary to test as much CsW's as possible, to see how this genetic disease is spread.
And of course in the meantime a lot of more research about DM is still needed!

14-11-2010, 23:30	#1
mijke Senior Member Join Date: Sep 2003 Location: Warnsveld Posts: 2,033	DM test results and breeders Reading other topics about DM on wolfdog, I did see a lot of blaming of breeders in relation of DM test results... But it is soooooo silly to blame specific breeders when it is known DM did appear in their lines. In first place you stimulate owners and breeders in future only to publish the " Free" results (because otherwise they will receive comments) And then we can never see how DM is spread in the breed! And second: Only since a short time we have the DM test for the CsW breed. (nobody even did know before that this disease was in the breed!) So in the past a lot of combinations can be made with a high risk for DM, without knowing by anybody.... I'll give you my personal example: I did import my CsW female from CZ. When she was grown up, we did see she had a good character, HD A and several good show results. (in that time dwarfism and DM test did not exist) And we did decide to breed with her. I did look for good combinations and for one of her litters I did use a male from SK. The last years I did spend a lot of time to get validated the Dwarfism and DM test for the CsW breed. And when these test were possible for CsW breed I also did test my (already sterilized) female. She was Free of Dwarfism and carrier of DM. From the litter with the SK male one of the offspring was carrier of DM. And 2 days ago I did receive the result of a female of this litter and she was affected. (DM/DM) So also the male from SK that I did use was unfortunately also carrier.. And it means also that I am also a breeder of an affected DM/DM CsW. So `breeder blamers` you also now can start shooting at me! Personal I only can hope that the affected female never will get the physical problems of DM. But I can´t change the history! Just like a lot of other breeders I did my best to make the best combinations for the breed with my female. I am convinced that in future more DNA test will be available for the CsW breed. And it will become more difficult to make the right combinations for the breed. (that will depend of a lot of factors) But I hope everybody realizes that it on that moment it will be also silly to blame breeders for combinations they did make in the past! On this moment only an extreme low percentage of the CsW breed is yet tested!!!! And when dog combinations for new litters are not tested, it does not mean there was/is NO DM in these lines...... So for now it is only important that as much as possible CsW's will be tested And again: DM is an old disease that exists in every breed and also in other not breed dogs Not all DM affected dogs get physical problems Probably creates a combination of more factors that a dog will get the physical problems Breeding of breed dogs is a closed system When higher homozygote in a breed : more genetic diseases, more behavior problems, less resistor, weaker performance, less vitality, more birth dead, and smaller litters Heterozygote is needed for a healthy population of a breed! So as told before in other topics, the advice of genetic specialists: Try to breed as less Affected dogs as possible But don't exclude dogs for breeding! Try to keep the gene poule as broadly (and maximize) as possible Everybody has to realize there is not any reason for "blind panic" about DM!! But also in CsW breed it seems to be "an old disease" that did start in the past. And probably it did start in earlier lines in countries of origin and a lot more CsW's can be Carrier or Affected. So it will be good to test a lot more CsW's for DM! Only then we can see how DM is spread in the breed and try to avoid that more Affected CsW's will be born! On this moment it would not be clever to make specific breeding rules based on the relative few CsW that have DM test results ! Especially when not everything is known about this disease. But for the future of the breed it is necessary to test as much CsW's as possible, to see how this genetic disease is spread. And of course in the meantime a lot of more research about DM is still needed! __________________ Vriendelijke groeten, Mijke PS: I am not a moderator anymore!!