Epilepsy and wolfdogs!?

[elf]

Envoyé par elf

Omega 3 supplementation may help your epileptic dog.


"Epilepsy Behav. 2009 Aug;15(4):527-8. Epub 2009 Jun 21.

Positive impact of omega-3 fatty acid supplementation in a dog with drug-resistant epilepsy: a case study.

Scorza FA, Cavalheiro EA, Arida RM, Terra VC, Scorza CA, Ribeiro MO, Cysneiros RM.

Disciplina de Neurologia Experimental, Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM), São Paulo, Brazil. [email protected]
Abstract

Epilepsy is the most common neurological disorder in both dogs and humans. Although the pharmacological options for treatment of epilepsies have increased, it has been reported that two-thirds of dogs with epilepsy are refractory to antiepileptic drug therapy. To our knowledge, there are no experimental studies in the literature that show an effect of omega-3 supplementation on epilepsy in dogs. Our case study describes the effectiveness of daily intake of a moderate amount of fish oil in a case of canine epilepsy."

Here are given quantities:

fish oil (oral omega-3 polyunsaturated fatty acids, 2 g/day)

Extract:

A 2-year-old female Great Dane with a history of recurrent seizures
was brought to a veterinary neurologist. Tonic–clonic seizures
occurred at a frequency of three times per month and were
characterized by facial automatisms, forelimb clonus, rearing and
falling, and loss of consciousness. After a detailed physical and neurological
examination, evaluation of hematology and serum biochemistry,
and magnetic resonance imaging of the brain, the
veterinarian diagnosed the condition as idiopathic epilepsy and began
treatment aimed at seizure control. A trial therapy with phenobarbital
(2.5 mg/kg, twice a day orally) failed to adequately control
the seizures: after 8 weeks of treatment there remained two seizure
episodes per month. Typically, potassium bromide is used to
supplement phenobarbital in refractory cases. However, in this
case, it was decided to supplement the dog’s diet with moderate
amounts of fish oil (oral omega-3 polyunsaturated fatty acids,
2 g/day). The frequency of the epileptic seizures markedly fell after
50 days of combination therapy with phenobarbital and omega-3
fatty acid. During the subsequent 18-month period, seizure frequency
fell to one per 3 months, a reduction of about 85%.