up date Dwarfism - Page 2

solowolf · 20-12-2008, 23:16

Quote:

Originally Posted by mijke

Dogs that don't have the right size for a CSW (to small) are not really dwarfs.
So Utrecht don't need EDTA blood of them

so what your saying it dosnt matter if they are carrier ???? pacino

mijke · 21-12-2008, 00:33

[quote=solowolf;179202]i offer you test from direct offspring of Chrop, i offer to bring this bitch to vet of your choice to europe, YOU REFUSE now without any bu..sh..t or feebile excuses tell us all WHY? [quote]

For your info I did not refuse anything, I even did not have contact with you. I only had not time to answer sooner in this topic.

But: First the university need to validate the test in the way Nebulosa did explain you again.

Only when this test validated for the CsW breed, all other owners can test their dog for this mutated gen to see if they are carriers.

But on this moment this is still not possible and that is all.

jmvdwiel · 21-12-2008, 01:31

a little thing about the genetics (probably unnescesary for most of the people here)

A dwarf is homozygote for the dwarg gen. (two gens for dwarf one inherited from the mother and one inherited from the father)
A carrier is heterozygoot for the dwarg gen and is healthy him/herself. it has a healthy gen and a dwarf gen (one inherited from the father or the mother)
a healthy dog doesn't carrie the dwarf gen, this dog has two healthy gens.

A dwarf dies or is recognised as a dog you do not breed with

If you breed with two carriers, a qwart of al the puppies is going to be a dwarf (statisticly), 1/2 is going to be a carier again, and another 1/4 are going to be healty dogs.
So to validate the test you must test the dwarf or the parents, if you test the other pups it could be that you wil test the healthy pup and so this test cannot be validated.

if you breed a carries with a healthy dog (without the gen) only healthy (1/2) and carries(1/2) are going to be born.

So if this test can be used with our breed, you can stil breed with al the carriers if the other dog is healthy(doesn't carry the gen) so no new dwarf wil be born. So no dogs has to be ruled out as a breeding dog that is good because there aren't that many dogs so that we can be very picky

21-12-2008, 00:33	#22
mijke Senior Member Join Date: Sep 2003 Location: Warnsveld Posts: 2,033	[quote=solowolf;179202]i offer you test from direct offspring of Chrop, i offer to bring this bitch to vet of your choice to europe, YOU REFUSE now without any bu..sh..t or feebile excuses tell us all WHY? [quote] For your info I did not refuse anything, I even did not have contact with you. I only had not time to answer sooner in this topic. But: First the university need to validate the test in the way Nebulosa did explain you again. Only when this test validated for the CsW breed, all other owners can test their dog for this mutated gen to see if they are carriers. But on this moment this is still not possible and that is all. __________________ Vriendelijke groeten, Mijke PS: I am not a moderator anymore!! Last edited by mijke; 21-12-2008 at 00:35.

21-12-2008, 01:31	#23
jmvdwiel Senior Member Join Date: Apr 2007 Posts: 1,061	a little thing about the genetics (probably unnescesary for most of the people here) A dwarf is homozygote for the dwarg gen. (two gens for dwarf one inherited from the mother and one inherited from the father) A carrier is heterozygoot for the dwarg gen and is healthy him/herself. it has a healthy gen and a dwarf gen (one inherited from the father or the mother) a healthy dog doesn't carrie the dwarf gen, this dog has two healthy gens. A dwarf dies or is recognised as a dog you do not breed with If you breed with two carriers, a qwart of al the puppies is going to be a dwarf (statisticly), 1/2 is going to be a carier again, and another 1/4 are going to be healty dogs. So to validate the test you must test the dwarf or the parents, if you test the other pups it could be that you wil test the healthy pup and so this test cannot be validated. if you breed a carries with a healthy dog (without the gen) only healthy (1/2) and carries(1/2) are going to be born. So if this test can be used with our breed, you can stil breed with al the carriers if the other dog is healthy(doesn't carry the gen) so no new dwarf wil be born. So no dogs has to be ruled out as a breeding dog that is good because there aren't that many dogs so that we can be very picky Last edited by jmvdwiel; 21-12-2008 at 11:20.